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Integration also amplifies the challenges of reproductive cohorts: high dimensionality under modest n, partially missing omics blocks (cycle cancellation, biopsy selection, embryo availability), center/protocol batch structure, and heterogeneous endpoints (biochemical pregnancy vs live birth vs cumulative live birth)

Despite the availability of several options to treat obesity, there remains a treatment gap for patients with moderate obesity who have tried lifestyle interventions but do not qualify for bariatric surgery

Creatine is renowned for enhancing exercise performance and improving body composition

But it didn't really work at all, so that was it